工作坊丨Synthetic Biology 101合成生化学轻松学！
原文链接丨Original Link
http://synbiobeta.com/education/quick-start-introduction-to-synthetic-biology/
生化创客听起来很酷炫
但对生物只有些许
or
甚至是没有相关了解
怎么办？
6月18日（周六）
给SZOIL 4个钟
生化知识轻松学
分分钟变身生化创客
课程信息
课程时间：
2016年6月18日（周六）14:00-18:00
课程地点：
深圳开放创新实验室（深圳市福田保税区市花路福年广场B4-531）
我们将使用一些现代的教具让你能够轻松的地理解这堂课。例如，我们对一些故事、例子和交叉引用进行了结构化梳理形成模块，来为课程内容讲解提供足够的支持。我们简化术语，在课堂中使用基本的文献来帮助你学习和理解最新的研究成果。核心课程能力会通过各种方式进行强化，包括互动性的问答。
本课程是专为对生物只有些许或者甚至是没有相关了解，但是在创造性问题解决方案、迭代、分类、及归档成果的共享工程技术有相关背景的人而设计的。我们将用计算机科学与工程的相关类比和故事来描述细胞，基因和生物作用，并突出这些系统之间的差异，无论是在物理层面和技术发展层面。这种方法有助于我们找到能够努力完善和提高合成生物学和进行高品质项目的之处。如果你已经对生物学有一定的理解、正在寻找合成生物学或生物技术相关的中高级课程，那么请来参加我们的课程。
合成生物学是由Dr. Josh Gilmore和Dr. John Cumbers共同编写的一个新型概念化课程。课程为非专业人士提供了一个合成生物学互动交流课堂。该课程针对在其他领域，如计算机科学技术专业人士而编写，了解更多生物学在执行任务、创造高附加值产品中所产生的力量。我们重点分析我们领域内研究学习的相似性及差异性，让课程能够被更多人所接受，更具有启发性和难忘性。
1.介绍合成生物学
我们将讨论生物学的核心原则，包括安全规范、术语、输入、输出和流程。我们将研发组织课程及适应于在总有例外的科学环境中工作。我们将通过总结讲解利用这些原则的一些简单但非常基础和必要的实验，为接下来的合成生物学的内容提供综合的方式做提前准备。
2.细胞是一个微观化工厂
细胞的功能和规则可以被认为是工厂的工人、机械以及管理，接受交货和工作订单，产品发货，并进行维修，升级和修改。从细胞功能的这种自上而下的分析，我们将用酶取代我们的机器，用小分子代替交货，用DNA及其调节物代替我们的管理。我们将简单了解不同类型的细胞通信如何在整个系统中运作。
3.结构与活性关系
随着我们深入研究细胞，我们看到每部分发挥功能的方式都与它的大小、形状及活性有关。移动，方向和细胞定位在功能上也起到关键作用。当我们发现多系统间在结构和功能上的相似性，我们可以完善我们对这些部件的分类。这些大类让我们可以进一步按类型和功能来系统化生物分子成为一个迅速扩大的工具包。
4.处理生物，细胞，基因和基因组
作为我们深入研究的细胞中，我们看到的方式各部分的功能是相关的它的大小，形状和活性。移动，方向和细胞定位在功能上也起到关键作用。当我们发现在结构上的相似性和跨多个系统的功能，我们可以提高我们的这些部件的分类。这些大类然后让我们来进一步组织按类型和功能的生物分子进入一个迅速扩大的工具包。
5.生物经济中的新型企业及技术
了解合成生物学初创公司和业内人士的概况。我们将概述在该领域的最新投资动向，这些公司都在做什么以及他们是如何做的。我们还将讨论新技术正如何改变生物技术的现状以及展望和预测未来技术的发展趋势。
6.着手进行生物设计
在生物实验室亲自动手体验。我们将为一个现有的生物传感器设计一个DNA电路，然后将该DNA转移到细菌细胞，并启动它来测试它。我们将让细胞在夜里生长，并在第二天把结果拍摄照片发送给您。
John Cumbers 丨 SynBioBeta创始人
John是SynBioBeta的创始人。SynBioBeta是合成生物学创业公司、行业和投资者的活动中心。 John是布朗大学分子生物学、细胞生物学以及生物化学博士。他同时也是苏格兰爱丁堡大学生物信息学硕士，英格兰赫尔大学计算机科学学士。2005年，他在布朗大学创立了iGEM大赛（国际基因工程机器大赛）团队，2006/2006年作为iGEM大赛大使来到中国，并且自2008年以来，在NASA Ames研究中心的工作研究合成生物学及空间资源利用。目前，他作为NASAAmes研究中心SpacePortal合作伙伴，领导行星可持续发展合作实验室（PlanetarySustainability Collaboratory）。在那里，他为地球和空间的可持续发展的承受能力带来新的技术。 2010年，John承办美国国家科学院Keck Futures Initiative工作坊，探讨合成生物学在NASA使命中所扮演的角色。
SynBioBeta是企业家，投资者，政策制定者和致力于合成生物学领域爱好者的领先社区。致力于讲述生物领域和企业的故事，搭建网络，并帮助他们成长。
每年会举办数次国际会议及活动，将整个社区聚集在一起，让大家都有机会面对面与构建和塑造生物经济的先驱进行交流——从风投者和天使到企业家和产业思想领袖等。
SynBioBeta提供了一个高度专业化的新闻摘要，博客，在线广告，以及展览赞助，同时还有专家主导的研究报告，课程和培训以及咨询服务。
交通方式
地铁：三号线益田站A出口乘坐26路、375路至绒花路口西抵达福田保税区三号门口，步行至SZOIL
公交：N9路、26路、52路、60路、62路、375路、385路、B618路、B820路等。
如有疑问，请联系：
Vicky Xie <vicky.xie@szoil.org>
+86 15814097397
▽
扫描以下二维码或点击阅读原文报名
Original Link丨
http://synbiobeta.com/education/quick-start-introduction-to-synthetic-biology/
Event Info
Date & Time: Jun 18, 2016, 14:00-18:00
Venue: SZOIL, B4-531, No.3 Shihua Road, Futian Bonded Area, Futian District, Shenzhen.
How Will The Course Be Taught?
We’ll be using a number of modern teachingaids to make it easy for you to get the most out of the course. For example,we’ve structured the modules in manageable segments with core stories,examples, and cross-references to back up the content being explained. We cutthrough the jargon and help you tackle the latest research by using primarilyliterature and industry copy in the class. The core course competencies arereinforced in a variety of ways, including interactive Q&A.
Who Should Take This Course?
This course is designed for people withlittle or no previous knowledge of biology but with some background in theshared engineering skillset of creative problem solving, iteration,classification, and archiving results. We will use analogies and stories fromcomputer science and engineering to describe how cells, genes and organismsfunction and highlight the differences between these systems, both on aphysical level and in terms of technological development. This approach helpsus find useful places to apply our effort to improve synthetic biology and tocraft high quality projects. If you already have an understanding of biologyand are looking for an intermediate or advanced courses in synthetic biology orbiotechnology then please contact us.
What Is The Course And Why Is It Unique?
Introduction to Synthetic Biology is a newcourse conceptualized and written by Dr. Josh Gilmore and Dr. John Cumbers. Thecourse, to be held in San Francisco , provides an interactive class insynthetic biology for non-experts. The course is written for tech-professionalsin other fields such as computer science, to learn about the growing power ofbiology to perform useful tasks and make high value products from drugs tospiders silk. We focus on analyzing the similarities and differences in ourfields of study to make these lessons accessible, inspirational, and memorable.
Course Outline
1. An Introduction To Synthetic Biology
We will discuss the core principles ofbiology, including safety, terminology, inputs, outputs and processes. We willdevelop a framework for organizing the lessons to come and adapt to working ina science that always finds room for exceptions. We will conclude by coveringsome simple, yet foundational experiments utilizing these principles thatprepare us for the integrated approach to synthetic biology that follows.
2. The Cell Is A Microscopic ChemicalFactory
Cell function and regulation can be thoughtof as the workers, machinery, and management of a factory, accepting deliveriesand work orders, shipping out product, and performing repairs, upgrades andmodifications. From this top-down analysis of cellular function, we willreplace our machinery with enzymes, our deliveries with small molecules, and ourmanagement with DNA and its regulators. We will take a brief look at howvarious types of cellular communication keeps the whole system running.
3. Structure-Activity Relationships
As we delve deeper into the cell, we seethat the way each part functions is correlated to it’s size, shape andactivity. Mobility, orientation, and cellular localization also play criticalroles in function. As we find similarities in structure and function acrossmultiple systems, we can improve our classification of these parts. These broadcategories then allow us to further organize biomolecules by type and functioninto a rapidly expanding toolkit.
4. Manipulating Organisms, Cells, Genes AndGenomes
As we delve deeper into the cell, we seethat the way each part functions is correlated to it’s size, shape andactivity. Mobility, orientation, and cellular localization also play criticalroles in function. As we find similarities in structure and function acrossmultiple systems, we can improve our classification of these parts. These broadcategories then allow us to further organize biomolecules by type and functioninto a rapidly expanding toolkit.
5. New Companies And Technologies In TheBioeconomy
Get an overview of synthetic biologystart-up companies and industry players. We’ll outline the recent investmenttrends in the field, what these companies are doing and how they are doing it.We’ll also discuss how new technologies are changing the landscape ofbiotechnology and look at predictions of future technologies to come.
6. Hands on Biological Design
Get a hands on experience in the biologylab. We’ll design a DNA circuit for a living biosensor and then transfer thatDNA into a bacterial cell and boot it up to test it. We’ll leave the cells togrow overnight and send you a photograph of your results the next day.
Instructors
John Cumbers丨Founder of SynBioBeta
John isthe founder of SynBioBeta, an activity hub for synthetic biology startupcompanies, industry and investors. He received his PhD in MolecularBiology, Cell Biology, and Biochemistry from Brown University. He has a mastersdegree in bioinformatics from the University of Edinburgh in Scotland and anundergraduate degree in computer science from the University of Hull inEngland. He founded the iGEM (International Genetically Engineered Machinescompetition) team at Brown University in 2005, was an iGEM ambassador to Chinain 2006/2007 and has been working in the field of synthetic biology andresource utilization in space at NASA Ames since 2008. He currently leadsthe Planetary Sustainability Collaboratory at the NASA Ames Space Portal wherehe works on partnerships that bring new technologies to bear on sustainabilitychallenges on Earth and in space. In 2010, John was the recipient of aNational Academies Keck Futures Initiative award to hold a workshop on the rolethat synthetic biology could play in NASA’s missions.
SynBioBeta
SynBioBeta is the leading community of entrepreneurs,investors, policymakers and enthusiasts devoted to the responsible growth ofthe synthetic biology field. We’re dedicated to telling the stories of thefield and companies involved, building their networks, and helping them grow.
Our international conferences and eventsbring the entire community together several times each year and give anyone theopportunity to meet with the bright minds building and shaping the bioeconomy —from venture capitalists and angel investors to entrepreneurs and industrythought leaders.
SynBioBeta offers a highly specialized newsdigest and blog, online advertisements, and exhibit sponsorships in addition toexpert-driven research reports, courses and training as well as consultingservices.
Transportation:
Metro：Exit A, Yitian Station, Line3. Take Bus No.26 or No.375 to Ronghua West Road and walk to SZOIL.
Bus：No.N 9, No. 26, No. 52, No. 60, No. 62, No. 375, No. 385, No. B618, No. B820 etc.
For any further info, please fee free to contact:
Vikcy Xie <vicky.xie@szoil.org>
+86 15814097397
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深圳开放创新实验室是由创客大爆炸和深圳市工业设计行业协会联合建设的国际创客开放平台和众创空间，也是深圳第一家经美国MIT 授权认证的Fablab国际微观装配实验室，以及美国麻省理工大学Fablab 2.0合作研发伙伴。深圳开放创新实验室主要包括开放创新中心、创业加速器和Fablab2.0研发制造三个功能板块，致力于发展、挖掘全球创客项目及产品，研发解决方案来连接大规模生产生态系统和服务于小型硬件创业者；进一步推进深圳在数字智能硬件的开发和生产制造的国际地位，结合新的开源方式以及深圳现有敏捷制造系统，将深圳打造成为未来智能硬件的硅谷。
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